Just wanted to report to Twonky and this forum: I have been a happy TwonkMedia user for years, serving Netgear and Streamium clients from a Linux server. I recently switched to a Windows-based server (for unrelated reasons), so I took a look at what else is out there.
I tried a couple, Windows Media Player 11 and Nero's offering included. None worked - either they worked with just one of the clients, or could not be found at all. They'd typically take a long time to index the library, and/or to start up, and/or to browse the collection from the clients. When something worked, I found it worked not better than with my Twonky server.
In short: I have happily renewed my Twonky license and remain a happy Mediaserver user.
Great job, Christian & Co!